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Ozempic Face: What It Is, Why It Happens, and How to Fix It

Posted September 08, 2025 in Non-Surgical Treatments

Young woman with a sunken face

After taking the leap and trying a GLP-1 medication, you’ve made major strides toward better health and increased confidence by losing weight. However, while you’re admiring how your clothes fit better, you may glance in the mirror and wonder why your face suddenly looks a bit older. How did that happen? This phenomenon has become so common that it now has a name: “Ozempic face.” In this blog, we’ll explore exactly what Ozempic face is, why it happens, and how to rejuvenate your appearance without surgery.

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Table of Contents

What Is Ozempic Face?

“Ozempic face” is a catchy term to describe a drawn, hollow, or prematurely aged facial appearance after significant weight loss. And while the name stems from the popular weight loss medication, this facial change is actually a side effect of rapid weight loss in general. The term was coined by a dermatologist who noticed an uptick in patients with concerns after weight loss with the help of Ozempic® (and other similar medications like Wegovy®, Zepbound®, and Mounjaro®), but the issue itself is nothing new.

In reality, anyone who experiences significant weight loss, regardless of whether it’s due to medication, dieting, or surgery, can develop these facial changes. You’ve lost fat all over, which is a bonus; however, it was that fat that gave your face a youthful, softer appearance. Now that it’s diminished, you’re left with sagging skin, fine lines, and maybe even changes to your skin tone and texture.

How Does Rapid Weight Loss Affect Your Face?

Your face changes as you lose weight because fat isn’t just stored in the belly, hips, or thighs. It also shapes your face, giving soft volume to your cheeks, temples, and under your eyes. When facial fat decreases quickly, several things happen:

Loss of Facial Volume

As you age, facial fat naturally decreases, and when you lose weight quickly, that fat rapidly decreases. If you think of facial fat as nature’s filler, you realize that when you lose that cushion of fat, the contours of your face change—sometimes dramatically. What was once a round or full face may now appear gaunt or overly defined, with prominent cheekbones or sunken eyes. While some people seek this “sculpted” look intentionally, too much volume loss can lead to a prematurely aged appearance.

Sagging Skin

Your skin is elastic, but it also has its limits. When you lose weight too quickly, your skin doesn’t always have time to “bounce back” and contract to your newly slimmer facial contours. This results in loose or sagging skin, especially in your lower face and jawline. Factors like age, skin quality, and how long you carried extra weight also play a role in how well your skin bounces back.

More Pronounced Wrinkles

As fat disappears from under your skin, there’s less structural support to keep your skin smooth and supple. Wrinkles and fine lines that were once barely noticeable can become much more visible, particularly around your eyes, mouth, and forehead.

How to Fix Ozempic Face Without Surgery

If you’re struggling with Ozempic face, know that there are a wide variety of noninvasive solutions available to help restore a more youthful and refreshed appearance without reversing the weight loss progress you’ve made. Dr. Mark Chin at Aspire Medispa in Fresno offers several advanced aesthetic treatments designed to rejuvenate your face with natural-looking results.

Injectables for Volume and Smoothing

BOTOX® Cosmetic

BOTOX® Cosmetic is a popular neuromodulator that smooths dynamic lines and wrinkles, such as crow’s feet, “elevens,” and horizontal forehead lines, for a refreshed appearance.

JUVÉDERM®

The original in this family of hyaluronic acid-based fillers, JUVÉDERM® is used to restore lost volume in the face, targeting the nasolabial folds that extend from the corners of your nose to your mouth.

JUVÉDERM VOLUMA® XC

Specifically designed to restore volume in your midface and cheek area, JUVÉDERM VOLUMA® XC helps lift and contour your face to reverse sagging and hollowness caused by weight loss.

Trinity™ Plus

This powerful, noninvasive skin rejuvenation platform combines three technologies: intense pulsed light (IPL), radio frequency energy, and infrared light to address texture, tone, and skin laxity in a single treatment. Trinity™ Plus is ideal for improving your overall skin health and brightness.

Ultherapy®

Ultherapy® utilizes focused ultrasound energy to stimulate the production of collagen deep within your skin. It’s an excellent option for lifting and tightening your lower face, jawline, and neck without downtime or incisions, and the boost in collagen can improve the overall appearance of your skin.

Explore Nonsurgical Ozempic Face Treatments in Fresno

You’ve worked hard to achieve your weight loss goals, so now it’s time to focus on ensuring that your face reflects how good you feel inside. Aspire Medispa offers a full complement of nonsurgical facial rejuvenation options designed to address Ozempic face, age-related volume loss, and more. To schedule a consultation to learn which facial rejuvenation options are right for you, call Aspire Medispa today at (559) 435-8477 or complete the online contact form.